Sampson County is a county located in the U.S. state of North Carolina. As of 2000, the population was 60,161. Its county seat is Clinton.
The county was formed in 1784 from Duplin County. It was named after John Sampson, who was the first register of deeds of Duplin County and the first mayor of Wilmington, North Carolina.
Sampson County is the birthplace of William R. King, who after spending time in local government continued on to become the 13th US vice-president.
According to the U.S. Census Bureau, the county has a total area of 947 square miles, of which, 945 square miles of it is land and 2 square miles of it (0.21%) is water.
Sampson County is the second largest county, in land area, in North Carolina.
The county is drained by the Black and South Rivers, as well as Six Run Creek.